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In 1971, Judah Folkman published the first hypothesis that tumor growth is angiogenesis dependent, thus paving the way to the development of anti-angiogenic therapy.
The anti-angiogenic therapy is essentially based on the use of biological drugs or biotherapeutics (monoclonal antibodies and recombinant proteins).
Uemura A. et al. Progress in Retinal and Eye Research Feb 25:100954. (2021)
Italian patent n° 102020000028952, n° 102020000028964 and n° 102020000028976.
Tarallo V. et al, International Journal of Molecular Sciences 21:410 (2020)
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